Atopic Dermatitis (AD), Eczema – JEL0305
Atopic dermatitis (AD), also known as eczema, is a disease of unknown origin that usually starts in early infancy and can cause itching, lesions, dry skin as well as ‘lichenification’ of the skin, which involves thickening and an increase in skin marking. This can cause psychological trauma to patients, in addition to constant discomfort and pain, especially where AD affects the face.
AD is the most common skin disease in children, affecting approximately 15% – 20% of children and 1% – 3% of adults (Nutten S, 2015; Eichenfield LF et al, 2014).
The onset of the disease is often by 5 years of age, with the highest incidence occurring between the ages of 3 and 6 months although it can occur at any age (Eichenfield LF et al, 2014, Hanifin JM et al, 2007).
Early diagnosis and treatment are essential to avoid complications of AD and improve quality of life (Eichenfield LF et al, 2014).
The current treatments for AD carry significant safety risks, which limit their application to mainly moderate-to-severe patients.
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