THERAPEUTIC PIPELINE

Carocell Bio, the inflammation company, is developing novel medicines that have the potential to provide safer and more effective approaches to manage the inflammatory response.

Combining our proprietary, patented peptides with established nanoparticle technology enhances delivery into cells. The treatments are designed to be delivered topically, for example via a spray, rather than systemically and the peptides will be simply broken down into amino acids, so they are likely to provide a much safer option compared with existing therapies.

In a previous study by Carocell Bio, it was demonstrated that the peptides can be delivered into individual cells, can lower inflammation to normal levels, and can also prevent the re-activation of inflammation. Further testing in human inflammatory tissue biopsies is expected by end of Q1 2022.

Therapeutic Pipeline

peptide development

MODE OF ACTION

  • Unique MOA
  • Peptide + nanoparticle delivery
  • Blocks MAPK activation and reactivation
  • Reduces pro-inflammatory cytokine production

ADMINISTRATION

  • Topical, not systemic 
  • Sterile spray for scar prevention
  • Soothing, therapeutic creams for skin conditions
  • Gel/delayed release oral capsule for GI diseases

EFFICACY

  • Potent inflammation inhibitor
  • Ability to ‘halt’ inflammation at the top of the intracellular inflammation cascade

SAFETY

  • Simple safety profile 
  • Rapidly broken down into amino acids in serum should eliminate any toxicity

LEAD INDICATIONS

  • Novel treatment to prevent the formation of a scar after an operation
  • First line treatment for burns to reduce pain and prevent subsequent scarring

OUR RESEARCH

Find out more about our therapeutic peptides and how they can reduce inflammation in a host of serious inflammatory diseases.

PRESENTATION SLIDES

For further information and access to detailed documentation, please get in touch