THERAPEUTIC PIPELINE

Carocell Bio is revolutionising the treatment of inflammatory disease with its pipeline of next-generation anti-inflammatory peptides, to promote healthier healing and skin.

Its pipeline of products, meant for topical application to the skin, is designed to interrupt the inflammatory cascade – potentially providing safer and novel therapeutic options for patients. This includes preventing traumatic scarring following tumour resection as part of cancer treatment, the treatment of burns, and AD (eczema).

Combining our proprietary, patented peptides with established nanoparticle technology enhances skin penetration. The treatments are designed to be delivered topically, and potentially provide a much safer option compared with existing therapies.

In a previous study by Carocell Bio, it was demonstrated that the peptides can be delivered into individual cells from topical application, can lower inflammation to normal levels, and can also prevent the re-activation of inflammation.

Latest results show that the lead peptide, JEL3108, can significantly reduce the inflammation seen in human atopic dermatitis (AD, eczema) biopsies and human burn tissue biopsies.

Therapeutic Pipeline

carocell bio indications progress

MODE OF ACTION

  • Unique MOA
  • Peptide + nanoparticle delivery
  • Blocks MAPK activation and reactivation
  • Reduces pro-inflammatory cytokine production

ADMINISTRATION

  • Topical, not systemic 
  • Sterile spray for scar prevention
  • Soothing, therapeutic creams for skin conditions
  • Gel/delayed release oral capsule for GI diseases

EFFICACY

  • Potent inflammation inhibitor
  • Ability to ‘halt’ inflammation at the top of the intracellular inflammation cascade
  • Also prevents the activation of inflammation

SAFETY

  • Simple safety profile 
  • Rapidly broken down into amino acids in serum should eliminate any toxicity

LEAD INDICATIONS

  • Novel treatment to prevent the formation of a scar after an operation
  • First line treatment for burns to reduce pain and prevent subsequent scarring

OUR RESEARCH

Find out more about our therapeutic peptides and how they can reduce inflammation in a host of serious inflammatory diseases.

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PRESENTATION SLIDES

For further information and access to detailed documentation, please get in touch

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